Brain Stereotaxic is a precision device designed based on the principles of three-dimensional geometry and the anatomy of the nervous system. It accurately locates the position of internal brain structures in a three-dimensional coordinate system by means of reference points fixed outside the skull (usually marked points on the skull). The instrument usually consists of a frame with coordinate axes and a device for immobilizing the head of the animal or patient. By referring to a known brain atlas, a researcher or physician can calculate the coordinates of the brain region in which he or she wants to intervene, and then, using a system of guides on the localizer, guide surgical tools, electrodes, or syringes to the target location for manipulation, such as stimulation, sampling, injection, or destruction, without the need for direct visual observation.